Methyl 2-(5-((ethoxycarbonyl)amino)-1,2,4-thiadiazol-3-yl)acetate
1,2,4-Thiadiazole-3-acetic acid, 5-[(ethoxycarbonyl)amino]-, methyl ester
CAS: 150215-07-9
Molecular Formula: C8H11N3O4S
Methyl 2-(5-((ethoxycarbonyl)amino)-1,2,4-thiadiazol-3-yl)acetate - Names and Identifiers
Methyl 2-(5-((ethoxycarbonyl)amino)-1,2,4-thiadiazol-3-yl)acetate - Physico-chemical Properties
| Molecular Formula | C8H11N3O4S |
| Molar Mass | 245.26 |
| Density | 1.408 |
| pKa | 10.92±0.70(Predicted) |
| Refractive Index | 1.574 |
Methyl 2-(5-((ethoxycarbonyl)amino)-1,2,4-thiadiazol-3-yl)acetate - Introduction
1,2, 4-thiadiazole-3-acetic acid, 5-[(ethoxycarbonyl)amino]-, methyl ester (abbreviated as EGAMS) is an organic synthetic compound. Its chemical formula is C9H12N4O4 and its molecular weight is 244.21g/mol. The following is a description of the nature, use, formulation and safety information of EGAMS:
Nature:
1. Appearance: EGAMS is white or off-white crystalline powder.
2. Melting point: Its melting point range is 110-115 ° C.
3. Solubility: EGAMS is soluble in some organic solvents, such as methanol and chloroform, slightly soluble in water.
Use:
1. Chemical Synthesis: EGAMS can be used as a starting material or reagent for organic synthesis.
2. Pesticides: EGAMS can be used as fungicides and insecticides in agriculture.
Method:
The synthesis of EGAMS can be carried out by the following steps:
1. In an appropriate solvent, 1,2, 4-triazole is reacted with ethyl formate and aqueous ammonia.
2. Add an appropriate acid catalyst to carry out the condensation reaction.
3. Further washing and crystallization gave the pure EGAMS product.
Safety Information:
1. EGAMS should be stored in a cool, dry place, away from fire and oxidant.
2. During use, you must wear suitable protective gloves and glasses to avoid direct contact or inhalation.
3. If inhaled or exposed to EGAMS, rinse immediately with water and seek medical help.
4. EGAMS are organic compounds that may be toxic and should be used in accordance with safe operating procedures.
Nature:
1. Appearance: EGAMS is white or off-white crystalline powder.
2. Melting point: Its melting point range is 110-115 ° C.
3. Solubility: EGAMS is soluble in some organic solvents, such as methanol and chloroform, slightly soluble in water.
Use:
1. Chemical Synthesis: EGAMS can be used as a starting material or reagent for organic synthesis.
2. Pesticides: EGAMS can be used as fungicides and insecticides in agriculture.
Method:
The synthesis of EGAMS can be carried out by the following steps:
1. In an appropriate solvent, 1,2, 4-triazole is reacted with ethyl formate and aqueous ammonia.
2. Add an appropriate acid catalyst to carry out the condensation reaction.
3. Further washing and crystallization gave the pure EGAMS product.
Safety Information:
1. EGAMS should be stored in a cool, dry place, away from fire and oxidant.
2. During use, you must wear suitable protective gloves and glasses to avoid direct contact or inhalation.
3. If inhaled or exposed to EGAMS, rinse immediately with water and seek medical help.
4. EGAMS are organic compounds that may be toxic and should be used in accordance with safe operating procedures.
Last Update：2024-04-10 22:29:15
